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Anti-Lamin A/C Antibody (Clone#BEO-12)

Rabbit Monoclonal Antibody

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筛选器: All WB IHC ICC/IF IP FCM

BM4105

  • 50μl ¥1280 100μl ¥2180 150μl ¥2800
  • 货期: 现货
  • Western blot analysis of anti-LaminA/C antibody (BM4105). The sample well of each lane was loaded with 30 ug of sample under reducing conditions.
    Lane 1: human A431 whole cell lysates,
    Lane 2: human Hela whole cell lysates,
    Lane 3: human SK-OV-3 whole cell lysates.
    After electrophoresis, proteins were transferred to a membrane. Then the membrane was incubated with rabbit anti-LaminA/C antigen affinity purified monoclonal antibody (BM4105) at a dilution of 1:1000 and probed with a goat anti-rabbit IgG-HRP secondary antibody (Catalog # BA1054). The signal is developed using ECL Plus Western Blotting Substrate (Catalog # AR1197). A specific band was detected for LaminA/C at approximately 70-74 kDa. The expected band size for LaminA/C is at 74 kDa.

    all(13)
  • IHC analysis of Lamin A/C using anti-Lamin A/C antibody (BM4105).
    Lamin A/C was detected in a paraffin-embedded section of human breast cancer tissue. The tissue section was incubated with rabbit anti-Lamin A/C Antibody (BM4105) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.

    all(13)
  • IHC analysis of Lamin A/C using anti-Lamin A/C antibody (BM4105).
    Lamin A/C was detected in a paraffin-embedded section of human lung cancer tissue. The tissue section was incubated with rabbit anti-Lamin A/C Antibody (BM4105) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.

    all(13)
  • IHC analysis of Lamin A/C using anti-Lamin A/C antibody (BM4105).
    Lamin A/C was detected in a paraffin-embedded section of human esophageal cancer tissue. The tissue section was incubated with rabbit anti-Lamin A/C Antibody (BM4105) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.

    all(13)
  • IHC analysis of Lamin A/C using anti-Lamin A/C antibody (BM4105).
    Lamin A/C was detected in a paraffin-embedded section of human rectal cancer tissue. The tissue section was incubated with rabbit anti-Lamin A/C Antibody (BM4105) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.

    all(13)
  • IHC analysis of Lamin A/C using anti-Lamin A/C antibody (BM4105).
    Lamin A/C was detected in a paraffin-embedded section of human ovarian cancer tissue. The tissue section was incubated with rabbit anti-Lamin A/C Antibody (BM4105) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.

    all(13)
  • IHC analysis of Lamin A/C using anti-Lamin A/C antibody (BM4105).
    Lamin A/C was detected in a paraffin-embedded section of human tonsil tissue. The tissue section was incubated with rabbit anti-Lamin A/C Antibody (BM4105) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.

    all(13)
  • IHC analysis of Lamin A/C using anti-Lamin A/C antibody (BM4105).
    Lamin A/C was detected in a paraffin-embedded section of human liver cancer tissue. The tissue section was incubated with rabbit anti-Lamin A/C Antibody (BM4105) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.

    all(13)
  • IHC analysis of Lamin A/C using anti-Lamin A/C antibody (BM4105).
    Lamin A/C was detected in a paraffin-embedded section of human pancreas cancer tissue. The tissue section was incubated with rabbit anti-Lamin A/C Antibody (BM4105) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.

    all(13)
  • IHC analysis of Lamin A/C using anti-Lamin A/C antibody (BM4105).
    Lamin A/C was detected in a paraffin-embedded section of human stomach cancer tissue. The tissue section was incubated with rabbit anti-Lamin A/C Antibody (BM4105) at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit (Catalog # SV0002) with DAB (Catalog # AR1027) as the chromogen.

    all(13)
  • Immunofluorescent analysis using the Antibody.

    all(13)

产品简介 实验方案 引用文献 相关产品

产品简介>

产品名称
Anti-Lamin A/C Antibody (Clone#BEO-12)
规格/价格
50μl|1280 100μl|2180 150μl|2800
指标别称
70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; HGPS; IDC; lamin A; lamin A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; Prelamin A/C; PRO1; progerin
产品类型
Monoclonal
检验物种
human
应用范围
WB, IHC, ICC/IF, IP, FCM
基因名称
LMNA
克隆号
BEO-12
宿主
Rabbit
抗体亚型
IgG
免疫原
A synthesized peptide derived from human Lamin A/C
计算分子量
74 kDa
实际分子量
74 kDa
成分
500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化方式
Affinity-chromatography
产品形态
Liquid
保存条件
12 months from date of receipt,-20℃ as supplied.
背景资料
Lamins are structural protein components of the nuclear lamina, a protein network underlying the inner nuclear membrane that determines nuclear shape and size. There are three types of lamins, A,B and C. The lamin A/C (LMNA) gene contains 12 exons. Alternative splicing within exon 10 gives rise to two different mRNAs that code for pre-lamin A and lamin C. Lamin A/C is mapped to 1q21.2-q21.3 and mutations in this gene cause a variety of human diseases including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy, and Hutchinson-Gilford progeria syndrome. Lamin A/C deficiency is thus associated with both defective nuclear mechanics and impaired mechanically activated gene transcription.
Uniprot ID
P02545  
文献引用格式
Lamin A/C Antibody (Clone#BEO-12) (Boster Biological Technology, Wuhan, China. Catalog#BM4105)
应用释义
WB-蛋白质免疫印迹法; IHC- 免疫组织化学法; ICC/IF-免疫细胞荧光和免疫细胞化学; FCM-流式细胞术; ELISA-酶联免疫吸附测定; IP-免疫沉淀法; IF-免疫组织荧光法; ChIP-染色质免疫沉淀法;
基因名全称
Prelamin-A/C
推荐稀释比
Western blot (WB):1:500-2000
Immunohistochemistry (IHC):1:50-200
Immunocytochemistry/Immunofluorescence (ICC/IF):1:50-200
ImmunoPrecipitation (IP):1:20
Flow Cytometry (FCM):1:20

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    Anti-Lamin A/C Antibody (Clone#BEO-12)

    筛选器: All WB IHC ICC/IF IP FCM

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